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Pharmacokinetic and pharmacodynamic characterization of a new formulation containing synergistic proportions of interferons alpha-2b and gamma (HeberPAG®) in patients with mycosis fungoides: an open-label trial

  • Yanelda García-Vega1,
  • Idrian García-García1,
  • Sonia E Collazo-Caballero2,
  • Egla E Santely-Pravia2,
  • Alieski Cruz-Ramírez1,
  • Ángela D Tuero-Iglesias1,
  • Cristian Alfonso-Alvarado2,
  • Mileidys Cabrera-Placeres2,
  • Nailet Castro-Basart2,
  • Yaquelín Duncan-Roberts1,
  • Tania I Carballo-Treto3,
  • Josanne Soto-Matos3,
  • Yoandy Izquierdo-Toledo4,
  • Dania Vázquez-Blomquist4,
  • Elizeth García-Iglesias1 and
  • Iraldo Bello-Rivero1Email author
BMC Pharmacology and Toxicology201213:20

DOI: 10.1186/2050-6511-13-20

Received: 2 May 2012

Accepted: 21 December 2012

Published: 28 December 2012

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Open Peer Review reports

Pre-publication versions of this article and author comments to reviewers are available by contacting info@biomedcentral.com.

Original Submission
2 May 2012 Submitted Original manuscript
Resubmission - Version 2
Submitted Manuscript version 2
Resubmission - Version 3
Submitted Manuscript version 3
24 Aug 2012 Reviewed Reviewer Report - Hidefumi Wada
7 Oct 2012 Reviewed Reviewer Report - Mirte Malingre
29 Oct 2012 Author responded Author comments - Idrian Garcia-Garcia
Resubmission - Version 4
29 Oct 2012 Submitted Manuscript version 4
6 Dec 2012 Reviewed Reviewer Report - Mirte Malingre
11 Dec 2012 Reviewed Reviewer Report - Hidefumi Wada
Resubmission - Version 5
Submitted Manuscript version 5
Publishing
21 Dec 2012 Editorially accepted
28 Dec 2012 Article published 10.1186/2050-6511-13-20

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article.. All previous versions of the manuscript and all author responses to the reviewers are also available.

You can find further information about the peer review system here.

Authors’ Affiliations

(1)
Clinical Investigation Department, Center for Genetic Engineering and Biotechnology
(2)
“Hermanos Ameijeiras” Hospital, Dermatology Service
(3)
“Hermanos Ameijeiras” Hospital, Clinical Laboratory Service
(4)
Genomics Department, Center for Genetic Engineering and Biotechnology

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