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Molecular mechanism of cardol, isolated from Trigona incisa stingless bee propolis, induced apoptosis in the SW620 human colorectal cancer cell line

  • Paula Mariana Kustiawan1,
  • Kriengsak Lirdprapamongkol2,
  • Tanapat Palaga3,
  • Songchan Puthong4,
  • Preecha Phuwapraisirisan5,
  • Jisnuson Svasti2 and
  • Chanpen Chanchao6Email author
BMC Pharmacology and ToxicologyBMC series – open, inclusive and trusted201718:32

DOI: 10.1186/s40360-017-0139-4

Received: 31 July 2016

Accepted: 27 April 2017

Published: 4 May 2017

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Open Peer Review reports

Pre-publication versions of this article and author comments to reviewers are available by contacting info@biomedcentral.com.

Original Submission
31 Jul 2016 Submitted Original manuscript
30 Sep 2016 Reviewed Reviewer Report - Christopher Larbie
10 Nov 2016 Reviewed Reviewer Report - Venkata Kashyap Yellepeddi
11 Nov 2016 Author responded Author comments - Paula Mariana Kustiawan
Resubmission - Version 2
11 Nov 2016 Submitted Manuscript version 2
25 Jan 2017 Reviewed Reviewer Report - Ebru Yildirim
31 Jan 2017 Author responded Author comments - Paula Mariana Kustiawan
Resubmission - Version 3
31 Jan 2017 Submitted Manuscript version 3
20 Apr 2017 Author responded Author comments - Paula Mariana Kustiawan
Resubmission - Version 4
20 Apr 2017 Submitted Manuscript version 4
Publishing
27 Apr 2017 Editorially accepted
4 May 2017 Article published 10.1186/s40360-017-0139-4

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article and author comments to reviewers are available by contacting info@biomedcentral.com. All previous versions of the manuscript and all author responses to the reviewers are also available.

You can find further information about the peer review system here.

Authors’ Affiliations

(1)
Program in Biotechnology, Faculty of Science, Chulalongkorn University
(2)
Laboratory of Biochemistry, Chulabhorn Research Institute
(3)
Department of Microbiology, Faculty of Science, Chulalongkorn University
(4)
Institute Biotechnology and Genetic Engineering, Chulalongkorn University
(5)
Department of Chemistry, Faculty of Science, Chulalongkorn University
(6)
Department of Biology, Faculty of Science, Chulalongkorn University

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