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Table 1 Cocaine treatment regimens

From: Nitric oxide and histone deacetylases modulate cocaine-induced mu-opioid receptor levels in PC12 cells

Regimen

Description

SCT

A single dose of cocaine added to the cell culture media and not removed over the entire time-course

RIT

Three daily intermittent 30 min treatments applied to the cells separated by 1 h of regular cell culture media.

  1. PC12 cells were either given a single continuous treatment (SCT) or a repeated intermittent treatment (RIT) of cocaine.
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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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