|
ID
|
k (h-1)
|
V1 (l)
|
TBC (l h-1)
|
T1/2α (h)
|
T1/2β (h)
|
T1/2el (h)
|
Vss (l)
|
|---|
|
P1B
|
0.093
|
25.0
|
2.32
|
0.25
|
8.18
|
7.45
|
27.33
|
|
P2C
|
0.131
|
21.95
|
2.88
|
0.035
|
7.61
|
5.29
|
31.5
|
|
P3C
|
0.172
|
24.31
|
4.19
|
0.028
|
5.29
|
4.02
|
31.94
|
- t1/2α: half life of the alpha phase. t1/2β: half life of the beta phase. t1/2el: elimination half life. Vss: volume of distribution at steady state. V1: volume of distribution of the central compartment. TBC: Total body clearance. k: elimination rate constant. CV%: coefficient of variation. PX (1–5) patients 1–5.
