ID | k (h-1) | V1 (l) | TBC (l h-1) | T1/2α (h) | T1/2β (h) | T1/2el (h) | Vss (l) |
---|
P1B | 0.093 | 25.0 | 2.32 | 0.25 | 8.18 | 7.45 | 27.33 |
P2C | 0.131 | 21.95 | 2.88 | 0.035 | 7.61 | 5.29 | 31.5 |
P3C | 0.172 | 24.31 | 4.19 | 0.028 | 5.29 | 4.02 | 31.94 |
- t1/2α: half life of the alpha phase. t1/2β: half life of the beta phase. t1/2el: elimination half life. Vss: volume of distribution at steady state. V1: volume of distribution of the central compartment. TBC: Total body clearance. k: elimination rate constant. CV%: coefficient of variation. PX (1–5) patients 1–5.