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Table 1 Pharmacokinetic parameters calculated from the IFN alpha-2b and IFN gamma concentrations in serum (N = 12)

From: Pharmacokinetic and pharmacodynamic characterization of a new formulation containing synergistic proportions of interferons alpha-2b and gamma (HeberPAG®) in patients with mycosis fungoides: an open-label trial

Parameter

IFN alpha-2b

IFN gamma

Cmax (pg/mL)

263 ± 129

9.3 ± 7.0

Tmax (h)

12.0 ± 6.0

6.0 ± 0.8

λ (h-1)

0.16 ± 0.06

0.07 ± 0.05

t1/2 (h)

4.9 ± 1.4

13.4 ± 27.1

AUC (pg.h/mL)

4483 ± 4485

87.5 ± 89.9

MRT (h)

13.9 ± 7.9

13.5 ± 8.2

  1. Data are reported as mean ± standard deviation, except for Tmax expressed as median ± quartile range.