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Table 1 Pharmacokinetic parameters calculated from the IFN alpha-2b and IFN gamma concentrations in serum (N = 12)

From: Pharmacokinetic and pharmacodynamic characterization of a new formulation containing synergistic proportions of interferons alpha-2b and gamma (HeberPAG®) in patients with mycosis fungoides: an open-label trial

Parameter IFN alpha-2b IFN gamma
Cmax (pg/mL) 263 ± 129 9.3 ± 7.0
Tmax (h) 12.0 ± 6.0 6.0 ± 0.8
λ (h-1) 0.16 ± 0.06 0.07 ± 0.05
t1/2 (h) 4.9 ± 1.4 13.4 ± 27.1
AUC (pg.h/mL) 4483 ± 4485 87.5 ± 89.9
MRT (h) 13.9 ± 7.9 13.5 ± 8.2
  1. Data are reported as mean ± standard deviation, except for Tmax expressed as median ± quartile range.