Figure 2From: Microneedle pretreatment enhances the percutaneous permeation of hydrophilic compounds with high melting points Permeation profile. Permeation of diclofenac, ibuprofen, ketoprofen and paracetamol through bovine udder skin samples following pretreatment with 200 μm and 300 μm microneedles in comparison to untreated control skin (n = 5–6); mean + SEM.Back to article page