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Figure 3 | BMC Pharmacology and Toxicology

Figure 3

From: Decreased cervical epithelial sensitivity to nonoxynol-9 (N-9) after four daily applications in a murine model of topical vaginal microbicide safety

Figure 3

Cervical epithelial damage is still apparent after two daily exposures to N-9. Mice were exposed twice to unformulated 1% N-9 and sacrificed after the indicated post-exposure intervals following the second exposure. H&E-stained tissue sections (shown at 40x magnification) were assessed for vaginal (A, C, E, G) and cervical (B, D, F, H) epithelial toxicity and scored. The tissue damage score (see also Table1) is shown in the lower right corner of each panel.

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