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Figure 9 | BMC Pharmacology and Toxicology

Figure 9

From: 3-D DNA methylation phenotypes correlate with cytotoxicity levels in prostate and liver cancer cell models

Figure 9

Low-intesity MeC and low-intesity DAPI site distribution for equitoxic drug concentrations. For the two cell lines, the responding distributions of LIM and LID sites are quite similar between equitoxic drug concentrations: LID distributions did not notably vary between the two concentrations as much as LIM distributions did between IC10 and IC50 concentrations. However, a slight difference in LIM distribution was measured for DU145 at IC50: at 500 μM LIM distribution seemed more similar to distribution at IC10.

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