|
Guideline-recommended vancomycin dosing
|
0.91
|
0.53-1.56
|
|
Vancomycin duration > 15 days
|
3.65
|
2.16-6.17
|
|
Weight greater than 100 kilograms
|
2.08
|
1.18-3.67
|
|
Pitt Bacteremia Score of four or greater
|
3.80
|
2.17-6.63
|
|
Vancomycin trough greater than 20 mcg/ml
|
2.51
|
1.28-4.92
|
|
Age greater than 52 years
|
2.40
|
1.38-4.15
|
|
Intensive care unit resident
|
3.64
|
2.15-6.18
|
|
Concomitant nephrotoxin
|
2.08
|
1.24-3.49
|
|
Male gender
|
1.04
|
0.56-1.57
|
|
Charlson comorbidity index 5 or greater
|
1.14
|
0.57-2.27
|
|
Baseline serum creatinine greater than 1.0 mg/dL
|
0.94
|
0.56-1.57
|
