In utero exposure to low dose arsenic via drinking water impairs early life lung mechanics in mice

Table 1 Maternal and birth outcomes for C57BL/6J dams exposed to 0 (control), 10 or 100μg/L arsenic via drinking water (mean ± SD)

	Control	10μg/L As	100μg/L As
Maternal water consumption (mL/day)	5.11 ± 1.41	4.97 ± 1.36	4.91 ± 1.33
Gestation period (days)	20.1 ± 0.92	20.4 ± 0.88	20.0 ± 0.81
Litter size (pups/dam)	5.63 ± 1.98	4.79 ± 1.87	5.54 ± 2.23
Birth weight (g)	1.34 ± 0.16	1.35 ± 0.19	1.27 ± 0.18 *
Birth length (mm)	29.1 ± 1.74	28.8 ± 1.94	28.4 ± 1.90 *

There were no differences in maternal water consumption, gestation period or litter size between control and arsenic exposed mice. Offspring exposed to 100μg/L arsenic were born significantly smaller than control mice in both weight and length (* indicates significantly different to controls).

ISSN: 2050-6511