Safety, tolerability, pharmacokinetics and pharmacodynamics of GSK2239633, a CC-chemokine receptor 4 antagonist, in healthy male subjects: results from an open-label and from a randomised study

Table 1 Summary of subjects demographic characteristics

Demographics	Microdose intravenous study (n = 6)	Single oral dose study (n = 24)
Age, years; Mean [range]	22.7 [20.0–26.0]	37.2 [20.0–65.0]
Sex; n (%)
Male	6 (100%)	24 (100%)
Height, cm; Mean [range]	180.0 [172.0–187.0]	180.5 [163.0–197.0])
Weight, kg; Mean [range]	71.8 [60.1–85.5]	81.0 [65.7–106.0]
Body mass index, kg/m²; Mean [range]	22.1 [19.3–24.6]	24.9 [19.8–29.1]
Ethnicity; n (%)
Hispanic or Latino	0	1 (4%)
Not Hispanic or Latino	6 (100%)	23 (96%)
Race; n (%)^a
White-White/Caucasian/European heritage	6 (100%)	20 (83%)
White-Arabic/North African heritage	0	1 (4%)
Asian-Central/South Asian heritage	0	1 (4%)
Asian-South East Asian heritage	0	2 (8%)

ISSN: 2050-6511