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Table 1 Urea synthesis (mg/dL mg -1 , produced over 50 min) by liver tissue treated with atorvastatin

From: Bioenergetic study of murine hepatic tissue treated in vitro with atorvastatin

Untreated (n =6) Treated (n =6) P-value
0.061 ± 0.020 0.072 ± 0.022 0.3866
  1. Liver specimens were incubated at 37°C in KH buffer with and without 1.0 μM atorvastatin for 6 hr. Every 60 min, specimens were removed from the incubation solutions and placed in 1.0 mL KH buffer supplemented with 10 mM NH4Cl and 2.5 mM ornithine. The solutions were then analyzed for urea at min 50. The values are mean ± SD for hr 1 to 6.
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