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Table 1 Coordinates of PK parameters and dialysis procedure of our patient undergoing extended dialysis compared to the data from patients undergoing intermittent hemodialysis and CVVH from the literature

From: Cotrimoxazole plasma levels, dialyzer clearance and total removal by extended dialysis in a patient with acute kidney injury: risk of under-dosing using current dosing recommendations

TMP /SMX

ED

IHD [[13]]

CVVHDF [[3]]

n

1

16

2

Administred dose (mg)

800/4000

160/800

160/800

Cmax (mg/l)

7.51/80.8

1.93/41.8

3.73/33.4

Blood flow (ml/min)

140

200

150 & 180

Dialyzer clearance (ml/min)

94/51

38/42

26/29

Dialyzer surface (m2)

1.3

1.0

1.8

Dialyzer

Polysulphone

Cuprophane

Polysuphone

Treatment time (min)

442

240

Not reported