From: Role of astrocytes in manganese mediated neurotoxicity
Name of transporter | Â | Changes down (down-regulation) mediated by manganese | Cellular localization | References |
---|---|---|---|---|
Glutamine transporter | System | Â | Â | Â |
SNAT3 | System N | mRNA and protein expression; function(uptake and efflux) | astrocytes | |
SNAT2 | System A | mRNA and protein expression | astrocytes | [81] |
ASCT2 | System ASC | protein expression; function (uptake and efflux) | astrocytes | [81] |
LAT2 | System L | mRNA and protein expression; function (uptake) | astrocytes endothelial cells | [81] |
Glutamine transporter | ||||
GLAST | Â | protein expression; function (uptake) | astrocytes | |
GLT-1 | Â | mRNA and protein expression; function (uptake) | astrocytes |