Parameters
| |
Groupings
| |
---|
Lean control
|
ZDF control
|
CNX-011-67 (5 mg/kg)
|
---|
HbA1c
|
3.84 ± 0.08
|
5.50 ± 0.30
|
5.18 ± 0.11
|
Fructosamine
|
92.47 ± 10.68
|
236.36 ± 19.08
|
111.25 ± 10.61**
|
HOMA-IR
|
2.16 ± 0.74
|
64.26 ± 6.18
|
41.82 ± 2.59*
|
HOMA-beta
|
117.34 ± 39.35
|
1520.20 ± 227.30
|
2206.79 ± 418.69
|
PDX1 positive cells
|
650 ± 49
|
461 ± 47.50
|
589 ± 43
|
Apoptotic cells
|
00 ± 00
|
47 ± 8.7
|
29 ± 4.6
|
- Data in all panels are mean ± SEM (n = 10/group). Statistical comparison was conducted by One-way ANOVA with Dunnett’s post test correction to arrive at the significance level when compared with ZDF control. (*p < 0.05 and **p < 0.01).