Figure 8
From: Quantitation of small intestinal permeability during normal human drug absorption
Comparison of intestinal absorption rate for DC and AM models with T D = 200 minutes. The DC model rate of absorption (red) was generated for a high permeability solute (P = 4.17 x 10-4 cm/sec, Figure 8 A) and a low permeability solute (P = 0.00417 x 10-4 cm/sec, Figure 8 B) with the rest of conditions the same as in Figure 5. Then the AM model parameters that provided the best fit to the DC model were determined and the AM absorption rate (blue) plotted. See Table 1 for tabulation of the AM parameters.