Table 1 Comparison of “averaged” (AM) and dispersion convection (DC) absorption rates
From: Quantitation of small intestinal permeability during normal human drug absorption
DC Model | AM Model | |||||
|---|---|---|---|---|---|---|
PDC (10-4 cm/sec) | TD (min) | TG(min) | Fr. Absorb | PAM(10-4 cm/sec) | TG (min) | Fr. Absorb |
4.167 | 200 | 15 | .987 | 4.77 | 17.2 | .989 |
0.4167 | 200 | 15 | 0.600 | 0.493 | 18.56 | 0.604 |
0.04167 | 200 | 15 | 0.109 | 0.0514 | 19.76 | 0.111 |
0.004167 | 200 | 15 | 0.0119 | 0.00517 | 19.9 | .012 |
4.167 | 1000 | 15 | 0.999 | 4.167 | 15 | 0.999 |
0.4167 | 1000 | 15 | 0.658 | 0.522 | 20.8 | 0.690 |
0.04167 | 1000 | 15 | 0.111 | 0.0645 | 29 | 0.121 |
0.004167 | 1000 | 15 | 0.0119 | 0.0067 | 30 | 0.0129 |
4.167 | 200 | 60 | 0.997 | 4.155 | 60.0 | 0.997 |
0.04167 | 200 | 60 | 0.109 | 0.062 | 86 | 0.107 |
4.167 | 1000 | 60 | 0.999 | 4.167 | 60.0 | 0.999 |
0.04167 | 1000 | 60 | 0.112 | 0.0879 | 114.5 | 0.121 |