TY - JOUR AU - Choi, D. W. AU - Farb, D. H. AU - Fischbach, G. D. PY - 1977 DA - 1977// TI - Chlordiazepoxide selectively augments GABA action in spinal cord cell cultures JO - Nature VL - 269 UR - https://doi.org/10.1038/269342a0 DO - 10.1038/269342a0 ID - Choi1977 ER - TY - JOUR AU - Borden, L. A. AU - Czajkowski, C. AU - Chan, C. Y. AU - Farb, D. H. PY - 1984 DA - 1984// TI - Benzodiazepine receptor synthesis and degradation by neurons in culture JO - Science VL - 226 UR - https://doi.org/10.1126/science.6093257 DO - 10.1126/science.6093257 ID - Borden1984 ER - TY - JOUR AU - Lippa, A. AU - Czobor, P. AU - Stark, J. AU - Beer, B. AU - Kostakis, E. AU - Gravielle, M. AU - Bandyopadhyay, S. AU - Russek, S. J. AU - Gibbs, T. T. AU - Farb, D. H. AU - Skolnick, P. PY - 2005 DA - 2005// TI - Selective anxiolysis produced by ocinaplon, a GABAA receptor modulator JO - Proc Natl Acad Sci U S A VL - 102 UR - https://doi.org/10.1073/pnas.0502579102 DO - 10.1073/pnas.0502579102 ID - Lippa2005 ER - TY - JOUR AU - Wu, F. S. AU - Gibbs, T. T. AU - Farb, D. H. PY - 1991 DA - 1991// TI - Pregnenolone sulfate: a positive allosteric modulator at the N-methyl-D-aspartate receptor JO - Mol Pharmacol VL - 40 ID - Wu1991 ER - TY - JOUR AU - Kostakis, E. AU - Smith, C. AU - Jang, M. -. K. AU - Martin, S. C. AU - Richards, K. G. AU - Russek, S. J. AU - Gibbs, T. T. AU - Farb, D. H. PY - 2013 DA - 2013// TI - The Neuroactive Steroid Pregnenolone Sulfate Stimulates Trafficking of Functional NMDA Receptors to the Cell Surface via a Non-Canonical G-Protein and Ca++ Dependent Mechanism JO - Mol Pharmacol VL - 8 UR - https://doi.org/10.1124/mol.113.085696 DO - 10.1124/mol.113.085696 ID - Kostakis2013 ER - TY - CHAP AU - Desbiens, S. AU - Farb, D. H. ED - Shayne, G. PY - 2012 DA - 2012// TI - Medicine and Pathology – Current Needs for New Therapeutic Agents and Discovery Strategies – A Systems Pharmacology Approach. Chapter 1 BT - Development of Therapeutic Agents ID - Desbiens2012 ER - TY - JOUR AU - Alberts, B. PY - 2013 DA - 2013// TI - Impact factor distortions JO - Science VL - 340 UR - https://doi.org/10.1126/science.1240319 DO - 10.1126/science.1240319 ID - Alberts2013 ER - TY - JOUR AU - Simons, K. PY - 2008 DA - 2008// TI - The misused impact factor JO - Science VL - 322 UR - https://doi.org/10.1126/science.1165316 DO - 10.1126/science.1165316 ID - Simons2008 ER - TY - JOUR AU - Begley, C. G. AU - Ellis, L. PY - 2012 DA - 2012// TI - Raise standards for preclinical cancer research JO - Nature VL - 483 UR - https://doi.org/10.1038/483531a DO - 10.1038/483531a ID - Begley2012 ER - TY - JOUR AU - Wang, C. I. AU - Lewis, R. J. PY - 2013 DA - 2013// TI - Emerging opportunities for allosteric modulation of G-protein coupled receptors JO - Biochem Pharmacol VL - 85 UR - https://doi.org/10.1016/j.bcp.2012.09.001 DO - 10.1016/j.bcp.2012.09.001 ID - Wang2013 ER - TY - JOUR AU - Möhler, H. AU - Okada, T. PY - 1977 DA - 1977// TI - Benzodiazepine receptor: demonstration in the central nervous system JO - Science VL - 198 UR - https://doi.org/10.1126/science.918669 DO - 10.1126/science.918669 ID - Möhler1977 ER - TY - JOUR AU - Skolnick, P. PY - 2012 DA - 2012// TI - Anxioselective anxiolytics: on a quest for the Holy Grail JO - Trends Pharmacol Sci VL - 33 UR - https://doi.org/10.1016/j.tips.2012.08.003 DO - 10.1016/j.tips.2012.08.003 ID - Skolnick2012 ER - TY - JOUR AU - Kirschner, M. AU - Gerhart, J. AU - Mitchison, T. PY - 2000 DA - 2000// TI - Molecular “vitalism” JO - Cell VL - 100 UR - https://doi.org/10.1016/S0092-8674(00)81685-2 DO - 10.1016/S0092-8674(00)81685-2 ID - Kirschner2000 ER - TY - JOUR AU - Pei, Y. AU - Dong, S. AU - Roth, B. L. PY - 2010 DA - 2010// TI - Generation of designer receptors exclusively activated by designer drugs (DREADDs) using directed molecular evolution JO - Curr Protoc Neurosci VL - Chapter 4 ID - Pei2010 ER - TY - JOUR AU - Rupaimoole, R. AU - Han, H. D. AU - Lopez-Berestein, G. AU - Sood, A. K. PY - 2011 DA - 2011// TI - MicroRNA therapeutics: principles, expectations, and challenges JO - Chin J Cancer VL - 30 UR - https://doi.org/10.5732/cjc.011.10186 DO - 10.5732/cjc.011.10186 ID - Rupaimoole2011 ER - TY - JOUR AU - Jimenez-Mateos, E. M. AU - Henshall, D. C. PY - 2013 DA - 2013// TI - Epilepsy and microRNA JO - Neuroscience VL - 238 UR - https://doi.org/10.1016/j.neuroscience.2013.02.027 DO - 10.1016/j.neuroscience.2013.02.027 ID - Jimenez-Mateos2013 ER - TY - JOUR AU - Aston-Jones, G. AU - Deisseroth, K. PY - 2013 DA - 2013// TI - Recent advances in optogenetics and pharmacogenetics JO - Brain Res VL - 1511 UR - https://doi.org/10.1016/j.brainres.2013.01.026 DO - 10.1016/j.brainres.2013.01.026 ID - Aston-Jones2013 ER - TY - STD TI - National Center for Advancing Translational Sciences (NCATS): Available at: http://www.ncats.nih.gov UR - http://www.ncats.nih.gov ID - ref18 ER - TY - STD TI - The pre-publication history for this paper can be accessed here:http://www.biomedcentral.com/2050-6511/14/42/prepub UR - http://www.biomedcentral.com/2050-6511/14/42/prepub ID - ref19 ER -