Figure 1From: Assessing the translatability of In vivo cardiotoxicity mechanisms to In vitro models using causal reasoning Ability of CRE to reveal the similar molecular mechanisms of Isoprenaline induced cardiac hypertrophy based on rat (A) and mouse (B) independent experiments. Both models show similar molecular mechanisms mostly known for their role in hypertrophic cardiomyopathy. (Blue = predicted decrease, Yellow = predicted increase).Back to article page