Table 1 Precision and accuracy of the CR8 analysis (n = 3-5 each)
From: Pharmacokinetics and biodistribution of the cyclin-dependent kinase inhibitor -CR8- in mice
Concentration (μg/ml) | Precision (%) | Accuracy (%) | ||||
|---|---|---|---|---|---|---|
Between batch | ||||||
0.1 (LLOQ) | 3.7 | −13.3 | ||||
0.75 (QC1) | 7.7 | −2.0 | ||||
1.5 (QC2) | 6.9 | −3.8 | ||||
3.5 (QC3) | 4.9 | −4.4 | ||||
7.0 (QC4) | 3.3 | −5.3 | ||||
Within batch | Batch1 | Batch2 | Batch3 | Batch1 | Batch2 | Batch3 |
0.1 (LLOQ) | 4.2 | 3.4 | 4.8 | −16 | −15.4 | −8.5 |
0.75 (QC1) | 1.4 | 1.8 | 1.9 | 5.5 | −12.9 | −1.2 |
1.5 (QC2) | 1.5 | 1.7 | 0.8 | 4.3 | −6.7 | 3.0 |
3.5 (QC3) | 0.2 | 0.6 | 1.1 | −9.1 | −9.9 | −0.6 |
7.0 (QC4) | 0.8 | 2 | 1.3 | −3.5 | −7.4 | −4.1 |