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Table 4 Treatments commonly given to pregnant women for fetal benefit across the lifespan

From: Translational toxicology: a developmental focus for integrated research strategies

Disease/Indication Treatment Outcome Selected references
Neural tube defects Folate Reduction in risk of neural tube defects American Academy of Pediatrics Committee on Genetics [80]
U.S. Preventive Services Task Force [81]
Vision and cognitive function Docosahexaenoic acid (DHA) Support optimal visual and cognitive development Koletzko et al. [82]
Smoking Nicotine and/or N-acetylcysteine (NAC) Smoking cessation and/or chemoprevention of DNA (and other) damage Coleman et al. [83]
De Flora et al. [84]
Van Schooten et al. [85]
Maternal (and fetal)hypothyroidism Thyroid hormone therapy Avoid potential damage to neural development Abalovich et al. [86]
Rivkees & Mandel [87]
Shields et al. [88]
Kuppens et al. [89]
Lazarus et al. [90]
Cerebral palsy associated with preterm delivery Magnesium sulfate (MgSO4) Reduction in risk of cerebral palsy/ motor disorders in childhood Nelson & Grether [91]
Rouse et al. [92]
Conde-Agudelo & Romero [93]
Rouse [94]
Doyle et al. [95]