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Table 2 Individual pharmacokinetic parameters after oral administration of 25 mg DMAA (n = 7)

From: Physiological and pharmacokinetic effects of oral 1,3-dimethylamylamine administration in men

Subject

t1/2(hr)

tlag(hr)

tmax(hr)

Cmax(ng∙mL-1)

AUC0-∞(hr ng∙mL-1)

Vz/F (L)

Cl/F (L∙hr-1)

2

7.84

0.0

2.5

82.85

1281.88

203.04

17.94

3

6.92

0.25

5.0

108.1

893.23

257.13

25.75

4

6.57

0.25

6.0

60.23

1136.17

191.87

20.24

5

7.13

0.25

2.0

63.14

818.91

289.05

28.09

6

9.29

0.0

4.0

76.68

1456.19

211.73

15.79

7

11.79

0.25

3.0

68.07

1420.82

275.29

16.19

8

9.660

0.0

2.5

76.69

1424.23

223.55

16.15

Mean

8.449

0.143

3.57

76.54

1204.550

235.95

20.02

SD

1.87788

0.134

1.48

16.09

262.89

37.82

5.00

%CV

22.22

93.71

41.46

21.02

21.83

16.03

24.96