Table 4 Performance of the CASA (LBMPE1) and previously published FFM prediction equations in the NWAHS and FAMAS cohorts (age 50 years and over) across various body mass index groupings
From: Lean body mass: the development and validation of prediction equations in healthy adults
Mean (SD), kg | Mean error (95%CI), kg | P-value for mean error | R | ρ c(95% CI) [C b] | 95% limits of agreement | RMSE (95% CI), kg | |
|---|---|---|---|---|---|---|---|
BMI < 22 kg/m 2 (n = 135) | |||||||
LBM DXA | 42.45 (8.85) | ||||||
Heitmann equation | 44.85 (7.65) | 2.40 (1.85, 2.96) | <0.001 | 0.932* | 0.885 (0.847, 0.914) [0.949] | -4.12, 8.92 | 4.04 (3.21, 4.87) |
Janmahasatian equation | 43.72 (9.26) | 1.27 (0.77, 1.77) | <0.001 | 0.946* | 0.937 (0.914, 0.955) [0.989] | -4.65, 7.19 | 3.21 (2.55, 3.87) |
Deurenberg equation | 41.26 (8.04) | -1.18 (-1.77, -0.60) | <0.001 | 0.921* | 0.909 (0.876, 0.933) [0.986] | -8.04, 5.68 | 3.62 (2.86, 4.36) |
LBM PE1 | 43.52 (9.04) | 1.08 (0.57, 1.59) | <0.001 | 0.944* | 0.937 (0.913, 0.955) [0.993] | -4.92, 7.08 | 3.18 (2.53, 3.83) |
BMI 22- < 27 kg/m 2 (n = 847) | |||||||
LBM DXA | 47.45 (9.18) | ||||||
Heitmann equation | 50.67 (8.67) | 3.22 (2.99, 3.44) | <0.001 | 0.933* | 0.874 (0.860, 0.888) [0.938] | -3.42, 9.86 | 4.62 (4.26,4.98) |
Janmahasatian equation | 50.81 (9.71) | 3.36 (3.13, 3.59) | <0.001 | 0.937* | 0.880 (0.866, 0.893) [0.939] | -3.41, 10.1 | 4.77 (4.39, 5.15) |
Deurenberg equation | 47.91 (8.68) | 0.45 (0.22, 0.68) | 0.001 | 0.928* | 0.925 (0.915, 0.934) [0.997] | -6.42, 7.32 | 3.46 (3.16, 3.76) |
LBM PE1 | 48.64 (9.45) | 1.19 (0.96, 1.41) | <0.001 | 0.938* | 0.930 (0.920, 0.938) [0.992] | -5.41, 7.79 | 3.51 (3.20, 3.82) |
BMI 27- < 30 kg/m 2 (n = 596) | |||||||
LBM DXA | 52.00 (9.83) | ||||||
Heitmann equation | 55.65 (9.48) | 3.65 (3.36, 3.95) | <0.001 | 0.929* | 0.867 (0.847, 0.883) [0.933] | -3.65, 10.9 | 5.16 (4.69, 5.63) |
Janmahasatian equation | 56.11 (9.75) | 4.12 (3.83, 4.41) | <0.001 | 0.932* | 0.857 (0.837, 0.874) [0.919] | -3.08, 11.3 | 5.47 (4.97, 5.97) |
Deurenberg equation | 52.58 (9.23) | 0.59 (0.30, 0.88) | <0.001 | 0.928* | 0.925 (0.912, 0.935) [0.996] | -6.72, 7.90 | 3.70 (3.35, 4.05) |
LBM PE1 | 52.80 (9.69) | 0.81 (0.52, 1.09) | <0.001 | 0.933* | 0.929 (0.918, 0.939) [0.997] | -6.37, 7.99 | 3.67 (3.31, 4.03) |
BMI ≥30 kg/m 2 (n = 709) | |||||||
LBM DXA | 54.80 (11.7) | ||||||
Heitmann equation | 59.30 (11.7) | 4.50 (4.19, 4.80) | <0.001 | 0.937* | 0.867 (0.847, 0.883) [0.933] | -3.80, 12.8 | 6.12 (5.53, 6.71) |
Janmahasatian equation | 58.93 (11.0) | 4.13 (3.83, 4.43) | <0.001 | 0.937* | 0.857 (0.837, 0.974) [0.919] | -4.02, 12.3 | 5.80 (5.22, 6.38) |
Deurenberg equation | 54.07 (10.6) | -0.74 (-1.08, -0.39) | <0.001 | 0.917* | 0.925 (0.912, 0.935) [0.996] | -10.0, 8.55 | 4.70 (4.14, 5.26) |
LBM PE1 | 54.88 (11.3) | 0.08 (-0.23, 0.38) | 0.628 | 0.936* | 0.929 (0.918, 0.939) [0.997] | -8.15, 8.31 | 4.11 (3.61, 4.61) |