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Table 4 Performance of the CASA (LBMPE1) and previously published FFM prediction equations in the NWAHS and FAMAS cohorts (age 50 years and over) across various body mass index groupings

From: Lean body mass: the development and validation of prediction equations in healthy adults

  Mean (SD), kg Mean error (95%CI), kg P-value for mean error R ρ c(95% CI) [C b] 95% limits of agreement RMSE (95% CI), kg
BMI < 22 kg/m 2 (n = 135)        
LBM DXA 42.45 (8.85)       
Heitmann equation 44.85 (7.65) 2.40 (1.85, 2.96) <0.001 0.932* 0.885 (0.847, 0.914) [0.949] -4.12, 8.92 4.04 (3.21, 4.87)
Janmahasatian equation 43.72 (9.26) 1.27 (0.77, 1.77) <0.001 0.946* 0.937 (0.914, 0.955) [0.989] -4.65, 7.19 3.21 (2.55, 3.87)
Deurenberg equation 41.26 (8.04) -1.18 (-1.77, -0.60) <0.001 0.921* 0.909 (0.876, 0.933) [0.986] -8.04, 5.68 3.62 (2.86, 4.36)
LBM PE1 43.52 (9.04) 1.08 (0.57, 1.59) <0.001 0.944* 0.937 (0.913, 0.955) [0.993] -4.92, 7.08 3.18 (2.53, 3.83)
BMI 22- < 27 kg/m 2 (n = 847)        
LBM DXA 47.45 (9.18)       
Heitmann equation 50.67 (8.67) 3.22 (2.99, 3.44) <0.001 0.933* 0.874 (0.860, 0.888) [0.938] -3.42, 9.86 4.62 (4.26,4.98)
Janmahasatian equation 50.81 (9.71) 3.36 (3.13, 3.59) <0.001 0.937* 0.880 (0.866, 0.893) [0.939] -3.41, 10.1 4.77 (4.39, 5.15)
Deurenberg equation 47.91 (8.68) 0.45 (0.22, 0.68) 0.001 0.928* 0.925 (0.915, 0.934) [0.997] -6.42, 7.32 3.46 (3.16, 3.76)
LBM PE1 48.64 (9.45) 1.19 (0.96, 1.41) <0.001 0.938* 0.930 (0.920, 0.938) [0.992] -5.41, 7.79 3.51 (3.20, 3.82)
BMI 27- < 30 kg/m 2 (n = 596)        
LBM DXA 52.00 (9.83)       
Heitmann equation 55.65 (9.48) 3.65 (3.36, 3.95) <0.001 0.929* 0.867 (0.847, 0.883) [0.933] -3.65, 10.9 5.16 (4.69, 5.63)
Janmahasatian equation 56.11 (9.75) 4.12 (3.83, 4.41) <0.001 0.932* 0.857 (0.837, 0.874) [0.919] -3.08, 11.3 5.47 (4.97, 5.97)
Deurenberg equation 52.58 (9.23) 0.59 (0.30, 0.88) <0.001 0.928* 0.925 (0.912, 0.935) [0.996] -6.72, 7.90 3.70 (3.35, 4.05)
LBM PE1 52.80 (9.69) 0.81 (0.52, 1.09) <0.001 0.933* 0.929 (0.918, 0.939) [0.997] -6.37, 7.99 3.67 (3.31, 4.03)
BMI ≥30 kg/m 2 (n = 709)        
LBM DXA 54.80 (11.7)       
Heitmann equation 59.30 (11.7) 4.50 (4.19, 4.80) <0.001 0.937* 0.867 (0.847, 0.883) [0.933] -3.80, 12.8 6.12 (5.53, 6.71)
Janmahasatian equation 58.93 (11.0) 4.13 (3.83, 4.43) <0.001 0.937* 0.857 (0.837, 0.974) [0.919] -4.02, 12.3 5.80 (5.22, 6.38)
Deurenberg equation 54.07 (10.6) -0.74 (-1.08, -0.39) <0.001 0.917* 0.925 (0.912, 0.935) [0.996] -10.0, 8.55 4.70 (4.14, 5.26)
LBM PE1 54.88 (11.3) 0.08 (-0.23, 0.38) 0.628 0.936* 0.929 (0.918, 0.939) [0.997] -8.15, 8.31 4.11 (3.61, 4.61)
  1. Mean Error = DXA-PE; LBM, Lean Body Mass; DXA, Dual X-ray absorptiometry; RMSE, Root Mean Square Error; CI, Confidence interval; SD, Standard Deviation; R, Pearson Correlation; Cb = Bias Correction Factor; ρc = Concordance Correlation Coefficient.
  2. *p-value <0.001.