Figure 5From: Dipyrithione induces cell-cycle arrest and apoptosis in four cancer cell lines in vitro and inhibits tumor growth in a mouse model Effects of PTS2 treatment on caspase-9, caspase-3 and PARP. Cancer cells were treated with 2.5 μg/ml of PTS2 for 36 h, and then harvested. Western blot was used to determine proteolytic cleavage of caspase-9, caspase-3 and PARP. GAPDH was used as internal control. Results represent 3 independent experiments.Back to article page