Psychotropic drug use among people with dementia – a six-month follow-up study

Table 2 Multiple logistic regression regarding different psychotropic drug use

	*Odds ratio*	*95% confidence interval*	*p-value*
Antidepressants (N06A)
Male sex	0.727	0.381-1.385	0.332
Higher age	0.932	0.897-0.969	0.000
Moderate cognitive impairment^a	1.971	1.072-3.622	0.029
Mild cognitive impairment^a	0.933	0.460-1.894	0.848
Anxiolytics (N05B)
Male sex	0.522	0.181-1.505	0.229
Higher age	0.985	0.939-1.032	0.521
Moderate cognitive impairment^a	0.606	0.242-1.514	0.283
Mild cognitive impairment^a	1.331	0.509-3.481	0.560
Verbally disruptive/attention-	2.193	1.389-3.462	0.001
seeking behavior
Hypnotics and sedatives (N05C)
Male sex	1.769	0.917-3.413	0.089
Higher age	0.932	0.896-0.971	0.001
Moderate cognitive impairment^a	1.401	0.725-2.705	0.316
Mild cognitive impairment^a	3.627	1.685-7.810	0.001
Disoriented symptoms	1.545	1.169-2.041	0.002

Model Cox and Snell R²: 0.078, concordance between observed and predicted value: 65.4% (antidepressants): 0.070/85.5% (anxiolytics): 0.138/69.9% (hypnotics and sedatives). ^aCognitive score ranges from 0–27 points and a score of less than 24 is considered to indicate cognitive impairment. The scale is subdivided into three groups, 0–7 (severe cognitive impairment), 8–15 (moderate cognitive impairment) and 16–23 (mild cognitive impairment). Severe cognitive impairment is reference category.

ISSN: 2050-6511