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Table 1 Baseline characteristics of the statins and non-statin therapy groups

From: The association between statin therapy during intensive care unit stay and the incidence of venous thromboembolism: a propensity score-adjusted analysis

 

Statin (n =123)

Non-Statin (n = 675)

P-value

PS Adjusted P-Value

Age, mean ± SD, years

67.1 ± 11.3

47.1 ± 21.1

<0.001

0.59

APACHE II, mean ± SD

26.7 ± 8.1

23.5 ± 9.1

0.0002

0.90

GCS, mean ± SD,

9.0 ± 4.6

8.5 ± 4.0

0.20

0.96

Creatinine, mean ± SD, μmol/L*

228.0 ± 179.3

146.4 ± 133.8

<0.001

0.81

INR, mean ± SD

1.3 ± 0.5

1.4 ± 0.7

0.03

0.93

aPTT, mean ± SD,

43.4 ± 57.1

42.2 ± 60.8

0.83

1.00

Trauma, No%

3 (2.4)

223 (33.0)

<0.001

0.007

Femur fracture, No.%

2 (1.6)

50 (7.4)

0.02

0.45

Any central line present, No. (%)

91(74.0)

504 (74.7)

0.87

0.78

Bedridden for > 3 days, No. (%)

84 (68.3)

310 (45.9)

<0.001

0.44

Malignancy, No. (%)

8 (6.5)

86 (12.7)

0.05

0.77

Recent surgery, No. (%)

22 (17.9)

221(32.7)

0.001

0.65

Previous VTE, No. (%)

4 (3.3)

8 (1.2)

0.08

0.98

Hemodialysis catheter, No. (%)

33 (26.8)

125 (18.5)

0.03

0.71

Compression stocking, No. (%)

26 (21.1)

172 (25.5)

0.31

0.79

Sequential compression device, No. (%)

29 (23.6)

227 (33.6)

0.03

0.75

Unfractionated heparin, No. (%)

97 (78.9)

405 (60.0)

<0.001

0.58

Enoxaparin, No. (%)

16 (13.0)

212 (31.4)

<0.001

0.21

Platelet transfusion, No. (%)

12 (9.8)

132 (19.6)

0.009

0.97

  1. P-values are provided for the differences between the two groups significant before and after propensity score adjustment.
  2. APACHE: Acute physiology and chronic health evaluation, GCS: Glasgow coma scale, INR: International normalized ratio.
  3. aPTT: activated partial thromboplastin time, VTE: Venous thromboembolism, PS: propensity score.
  4. *To convert to conventional units in mg/dL, divide by 88.4.