Skip to main content

Table 1 Baseline characteristics of the statins and non-statin therapy groups

From: The association between statin therapy during intensive care unit stay and the incidence of venous thromboembolism: a propensity score-adjusted analysis

  Statin (n =123) Non-Statin (n = 675) P-value PS Adjusted P-Value
Age, mean ± SD, years 67.1 ± 11.3 47.1 ± 21.1 <0.001 0.59
APACHE II, mean ± SD 26.7 ± 8.1 23.5 ± 9.1 0.0002 0.90
GCS, mean ± SD, 9.0 ± 4.6 8.5 ± 4.0 0.20 0.96
Creatinine, mean ± SD, μmol/L* 228.0 ± 179.3 146.4 ± 133.8 <0.001 0.81
INR, mean ± SD 1.3 ± 0.5 1.4 ± 0.7 0.03 0.93
aPTT, mean ± SD, 43.4 ± 57.1 42.2 ± 60.8 0.83 1.00
Trauma, No% 3 (2.4) 223 (33.0) <0.001 0.007
Femur fracture, No.% 2 (1.6) 50 (7.4) 0.02 0.45
Any central line present, No. (%) 91(74.0) 504 (74.7) 0.87 0.78
Bedridden for > 3 days, No. (%) 84 (68.3) 310 (45.9) <0.001 0.44
Malignancy, No. (%) 8 (6.5) 86 (12.7) 0.05 0.77
Recent surgery, No. (%) 22 (17.9) 221(32.7) 0.001 0.65
Previous VTE, No. (%) 4 (3.3) 8 (1.2) 0.08 0.98
Hemodialysis catheter, No. (%) 33 (26.8) 125 (18.5) 0.03 0.71
Compression stocking, No. (%) 26 (21.1) 172 (25.5) 0.31 0.79
Sequential compression device, No. (%) 29 (23.6) 227 (33.6) 0.03 0.75
Unfractionated heparin, No. (%) 97 (78.9) 405 (60.0) <0.001 0.58
Enoxaparin, No. (%) 16 (13.0) 212 (31.4) <0.001 0.21
Platelet transfusion, No. (%) 12 (9.8) 132 (19.6) 0.009 0.97
  1. P-values are provided for the differences between the two groups significant before and after propensity score adjustment.
  2. APACHE: Acute physiology and chronic health evaluation, GCS: Glasgow coma scale, INR: International normalized ratio.
  3. aPTT: activated partial thromboplastin time, VTE: Venous thromboembolism, PS: propensity score.
  4. *To convert to conventional units in mg/dL, divide by 88.4.