Figure 3
From: Suppression of eukaryotic initiation factor 4E prevents chemotherapy-induced alopecia
Representative immunostaining of skin sections from Dox-treated shRNA/CAGs-RIK mice 3 days post-CyP. (A) Skin sections from mice of the indicated genotypes were processed for H&E staining, immunostained for the indicated proteins, or processed for visualization of apoptotic bodies as described in the Methods. Bars = 25 μm. (B) Percent of dystrophic hair follicles in mice of the indicated genotype taken 3 days after cyclophosphamide delivery. n = 3 mice. Bars denote S.E.M. (C) Average number of apoptotic cells per hair follicle. Five different fields (5 follicles/field) were analyzed from sections obtained from 2 different mice. Bars denote S.E.M.