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Table 3 PK parameters in patients with albumin >3 g/dL and <3 g/dL with statistically significant differences

From: Pharmacokinetics of piperacillin/tazobactam in cancer patients with hematological malignancies and febrile neutropenia after chemotherapy

PK parameter

Albumin <3 g/dL

Albumin >3 g/dL

Student’s t-test

P

C min (μg/mL)

8.3

20.4

4.5135

0.0305

Ke (h –1 )

0.7

0.4

-2.4515

0.0486

t 1/2 (h)

1.1

1.7

-2.5709

0.0245

  1. Mentioned on pages 6 and 8.