From: Pharmacokinetics of piperacillin/tazobactam in cancer patients with hematological malignancies and febrile neutropenia after chemotherapy
PK parameter
Albumin <3 g/dL
Albumin >3 g/dL
Student’s t-test
P
C min (μg/mL)
8.3
20.4
4.5135
0.0305
Ke (h –1 )
0.7
0.4
-2.4515
0.0486
t 1/2 (h)
1.1
1.7
-2.5709
0.0245