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Table 3 Effect of Gli on neutral lipid accumulation

From: Glibenclamide inhibits cell growth by inducing G0/G1 arrest in the human breast cancer cell line MDA-MB-231

Time (days)

Mean Fluorescence of Nile Red (% of control)

 

Gli

Na Butyrate

2

92.3 ± 4.7

134.3 ± 6.7 ***

3

99.3 ± 1.7

165.7 ± 7.3 ***

7

99.0 ± 10.1

192.7 ± 5.3 ***

  1. Gli: 25 μM glibenclamide. Na Butyrate: 10 mM Sodium butyrate as the positive control. p: NS Gli vs control; *** p < 0.001 butyrate vs control, One way ANOVA and Dunnet test.