Figure 1From: Pharmacokinetics of the soluble guanylate cyclase stimulator riociguat in individuals with hepatic impairmentBox-and-whisker plot of riociguat AUCnorm (kg·h/L) after a single oral dose of riociguat 1 mg. Box, 25th–75th percentile; vertical line, 10th–90th percentile; horizontal line, median; more extreme values are plotted as points; individuals eligible for pharmacokinetic analysis, n = 64; AUCnorm, area under the plasma concentration–time curve from time 0 to infinity divided by dose per kilogram of body weight for total riociguat.Back to article page