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Figure 1 | BMC Pharmacology and Toxicology

Figure 1

From: Pharmacokinetics of the soluble guanylate cyclase stimulator riociguat in individuals with hepatic impairment

Figure 1

Box-and-whisker plot of riociguat AUCnorm (kg·h/L) after a single oral dose of riociguat 1 mg. Box, 25th–75th percentile; vertical line, 10th–90th percentile; horizontal line, median; more extreme values are plotted as points; individuals eligible for pharmacokinetic analysis, n = 64; AUCnorm, area under the plasma concentration–time curve from time 0 to infinity divided by dose per kilogram of body weight for total riociguat.

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