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Table 2 Crude odds ratios for 1 month and 3 month discontinuation for factors such as: gender, age, deprivation score, prescription of anti-depressants and co-prescription of other therapeutic drug classes

From: Unplanned medication discontinuation as a potential pharmacovigilance signal: a nested young person cohort study

 

Duration of treatment

  

Duration of treatment

  
 

<1 month

≥1 month

OR

95% CI

<3 month

≥3 month

OR

95% CI

 

N = 41

N = 38

  

N = 61

N = 18

  

Gender n (%)

        

Female

33 (80.5%)

31 (81.6%)

Ref

 

48 (78.7%)

16 (88.9%)

Ref

 

Male

8 (19.5%)

7 (18.4%)

1.07

0.35–3.31

13 (21.3%)

2 (11.1%)

2.17

0.44– 10.65

Age bands n (%)

        

Children (under 17 years)

9 (22.0%)

15 (39.5%)

Ref

 

15 (24.6%)

9 (50.0%)

Ref

 

Young people (17-18 years)

32 (78.0%)

23 (60.5%)

2.32

0.87–6.21

46 (75.4%)

9 (50.0%)

3.07

1.03– 9.14

Deprivation SIMD 2006 n (%)

        

1-2

1 (2.4%)

7 (18.4%)

0.09

0.01–0.84

5 (8.2%)

3 (16.7%)

0.23

0.03-1.41

3-4

3 (7.3%)

4 (10.5%)

0.47

0.09–2.55

6 (9.8%)

1 (0.6%)

0.78

0.07– 8.93

5-6

12 (29.3%)

8 (21.1%)

0.94

0.28–3.09

15 (24.6%)

5 (27.8%)

0.39

0.08– 1.89

7-8

9 (22.0%)

9 (23.7%)

0.63

0.19–2.11

12 (19.7%)

6 (33.3%)

0.26

0.06– 1.23

9-10

16 (39.0%)

10 (26.3%)

Ref

 

23 (37.7%)

3 (16.7%)

Ref

 

Antidepressants n (%)

        

Yes

37 (90.2%)

28 (73.7%)

Ref

 

51 (83.6%)

14 (77.8%)

Ref

 

No

4 (9.8%)

10 (26.3%)

0.30

0.09–1.07

10 (16.4%)

4 (22.2%)

0.69

0.19– 2.52

Co-prescriptions issued n (%)

        

Yes

20 (48.8%)

4 (10.5%)

Ref

 

22 (36.1%)

2 (11.1%)

Ref

 

No

21 (51.2%)

34 (89.5%)

0.12

0.03–0.41

39 (63.9%)

16 (88.9%)

0.22

0.05– 1.06

  1. CI; Confidence Interval. OR; Odds Ratio.
  2. All percentage calculated from column total. SIMD: Scottish Index of Multiple Deprivation.
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