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Table 2 Crude odds ratios for 1 month and 3 month discontinuation for factors such as: gender, age, deprivation score, prescription of anti-depressants and co-prescription of other therapeutic drug classes

From: Unplanned medication discontinuation as a potential pharmacovigilance signal: a nested young person cohort study

  Duration of treatment    Duration of treatment   
  <1 month ≥1 month OR 95% CI <3 month ≥3 month OR 95% CI
  N = 41 N = 38    N = 61 N = 18   
Gender n (%)         
Female 33 (80.5%) 31 (81.6%) Ref   48 (78.7%) 16 (88.9%) Ref  
Male 8 (19.5%) 7 (18.4%) 1.07 0.35–3.31 13 (21.3%) 2 (11.1%) 2.17 0.44– 10.65
Age bands n (%)         
Children (under 17 years) 9 (22.0%) 15 (39.5%) Ref   15 (24.6%) 9 (50.0%) Ref  
Young people (17-18 years) 32 (78.0%) 23 (60.5%) 2.32 0.87–6.21 46 (75.4%) 9 (50.0%) 3.07 1.03– 9.14
Deprivation SIMD 2006 n (%)         
1-2 1 (2.4%) 7 (18.4%) 0.09 0.01–0.84 5 (8.2%) 3 (16.7%) 0.23 0.03-1.41
3-4 3 (7.3%) 4 (10.5%) 0.47 0.09–2.55 6 (9.8%) 1 (0.6%) 0.78 0.07– 8.93
5-6 12 (29.3%) 8 (21.1%) 0.94 0.28–3.09 15 (24.6%) 5 (27.8%) 0.39 0.08– 1.89
7-8 9 (22.0%) 9 (23.7%) 0.63 0.19–2.11 12 (19.7%) 6 (33.3%) 0.26 0.06– 1.23
9-10 16 (39.0%) 10 (26.3%) Ref   23 (37.7%) 3 (16.7%) Ref  
Antidepressants n (%)         
Yes 37 (90.2%) 28 (73.7%) Ref   51 (83.6%) 14 (77.8%) Ref  
No 4 (9.8%) 10 (26.3%) 0.30 0.09–1.07 10 (16.4%) 4 (22.2%) 0.69 0.19– 2.52
Co-prescriptions issued n (%)         
Yes 20 (48.8%) 4 (10.5%) Ref   22 (36.1%) 2 (11.1%) Ref  
No 21 (51.2%) 34 (89.5%) 0.12 0.03–0.41 39 (63.9%) 16 (88.9%) 0.22 0.05– 1.06
  1. CI; Confidence Interval. OR; Odds Ratio.
  2. All percentage calculated from column total. SIMD: Scottish Index of Multiple Deprivation.