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Table 3 Actual Symptoms and diagnoses recorded as Read codes by the treating primary care physician within 3 months of orlistat discontinuation (n = 79)

From: Unplanned medication discontinuation as a potential pharmacovigilance signal: a nested young person cohort study

System

Number of patients (%)

Symptoms

Frequency

Respiratory

8 (10.1%)

Influenza

3

Acute tonsillitis

3

Acute bronchitis and bronchiolitis

2

Asthma

1

Chest infection

1

Acute laryngitis and tracheitis

1

Upper respiratory infection

1

Cough

1

Respiratory symptom

1

Genitourinary

7 (8.9%)

Treatment via bladder catheter

5

Retention of urine

1

Urinary tract infection (UTI)

1

Suspected UTI

2

Cystitis

1

Dermatology

6 (7.6%)

Rash and other non-specific skin eruption

1

Dermatitis

1

Skin cyst

1

Chalazion (meibomian cyst)

1

Acne vulgaris

1

Unilateral mastalgia

1

Lump in breast

1

Psoriasis and similar disorders

1

Endocrine

6 (7.6%)

Obesity

4

Acquired hypothyroidism

2

Gynaecomastia

3

Obstetrics & Gynaecology

4 (5.1%)

Menorrhagia

1

Dysmenorrhoea

1

Spontaneous abortion

1

Codes related to spontaneous abortion

6

Polycystic ovarian syndrome

1

Gastrointestinal

4 (5.1%)

Non-infective gastritis

1

Gastritis

1

Abdominal pain

3

Abdominal discomfort

1

Irritable bowel syndrome

1

Musculoskeletal

4 (5.1%)

Backache

1

Pain in lumbar spine

1

Closed fracture of radius

1

Temporomandibular joint disorder

1

Arthralgia of knee

1

Mental health and behavioural

3 (3.8%)

Social phobias

4

Loss of confidence

1

Anxiety state

1

Depressed mood

4

At risk of deliberate self harm

1

Central nervous system

3 (3.8%)

In-coordination

1

Tiredness

1

Migraine

1

Headache

1

Infantile autism

1

Infection

3 (3.8%)

Viral infection

3