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Figure 4 | BMC Pharmacology and Toxicology

Figure 4

From: Whole adult organism transcriptional profiling of acute metal exposures in male Zebrafish

Figure 4

Enrichment analyses. A – Gene ontology term enrichment analysis for biological processes that are significantly (FDR = 0.1) enriched for up-regulated or down-regulated gene sets with at least 3 genes/transcripts present in a category to be considered significant by each metal. NOTE: The yellow highlight indicates that the enriched GO term “metabolic process” contained both up-regulated and down-regulated gene sets. B – KEGG pathway enrichment analysis for biological processes that are significantly (FDR = 0.1) enriched for up-regulated or down-regulated gene sets with at least 3 genes/transcripts present in a category to be considered significant by each metal. Metals listed on each heat map from left to right: nickel (Ni), cobalt (Co) and chromium (Cr) respectively. Color scale is log p-value of enrichment. White is for up-regulated gene sets and blue for down-regulated gene sets.

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