Skip to main content
Figure 6 | BMC Pharmacology and Toxicology

Figure 6

From: CNX-011-67, a novel GPR40 agonist, enhances glucose responsiveness, insulin secretion and islet insulin content in n-STZ rats and in islets from type 2 diabetic patients

Figure 6

Effect of CNX-011-67 on islet gene expression. mRNA levels of PDX1 (A), GCK (B), INS1 (C) and PC (D) in islets from sham control, n-STZ and n-STZ-CNX-011-67 rats were measured as mentined in the methods. The mRNA levels of all the genes were expressed relative to β-actin mRNA. Values represent mean ± S.E.M (n = 4). Statistical analysis was performed by Students t-test (Two-way, unpaired: * P < 0.05 and *** P < 0.001).

Back to article page

BMC Pharmacology and Toxicology

ISSN: 2050-6511

Contact us