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Table 2 Baseline individual factors associated with antihypertensive drug changes, CoLaus study

From: Antihypertensive drug treatment changes in the general population: the colaus study

  Continuers Combiners Switchers Discontinuers p-value
N 420 (54.4) 208 (26.9) 98 (12.7) 46 (6.0)  
Women (%) 213 (50.7) 93 (44.7) 50 (51.0) 15 (32.6) 0.08
Age (years) 60.2 ± 9.0 61.2 ± 8.9 59.2 ± 10.1 57.7 ± 8.2 0.06
Educational status (%)      
  Basic 94 (22.4) 46 (22.1) 22 (22.5) 10 (21.7)  
  Apprenticeship 186 (44.3) 90 (43.3) 37 (37.8) 18 (39.1) 0.90
  High school/college 91 (21.7) 47 (22.6) 26 (26.5) 9 (19.6)  
  University 49 (11.7) 25 (12.0) 13 (13.3) 9 (19.6)  
Smoking status (%)      
  Never 169 (40.2) 75 (36.1) 43 (43.9) 19 (41.3)  
  Former 160 (38.1) 94 (45.2) 35 (35.7) 18 (39.1) 0.67
  Current 91 (21.7) 39 (18.8) 20 (20.4) 9 (19.6)  
Physically active (%) 205 (48.8) 100 (48.1) 56 (57.1) 26 (56.5) 0.34
BMI (kg/m2) 28.4 ± 4.9 29 ± 4.4 27.9 ± 4.9 27.7 ± 4.2 0.15
BMI categories (%)      
  Normal 105 (25.0) 36 (17.3) 29 (29.6) 12 (26.1)  
  Overweight 181 (43.1) 92 (44.2) 41 (41.8) 26 (56.5) <0.05
  Obese 134 (31.9) 80 (38.5) 28 (28.6) 8 (17.4)  
Waist (cm) 97 ± 14 99 ± 14 95 ± 13 96 ± 12 0.13
Abdominal obesity (%) 219 (52.1) 121 (58.2) 48 (49.0) 16 (34.8) <0.05
Alcohol drinker (%) 301 (71.7) 160 (76.9) 74 (75.5) 31 (67.4) 0.39
Personal history of (%)      
  Myocardial infarction 27 (6.4) 16 (7.7) 2 (2.0) 1 (2.2) NA
  Stroke 11 (2.6) 8 (3.9) 5 (5.1) 1 (2.2) NA
  CVD 52 (12.4) 35 (16.8) 11 (11.2) 6 (13.0) 0.41
  Dyslipidemia 182 (43.3) 105 (50.5) 39 (39.8) 19 (41.3) 0.23
  Diabetes 64 (15.2) 31 (14.9) 10 (10.2) 4 (8.7) 0.41
Family history of (%)      
  Myocardial infarction 110 (26.2) 44 (21.2) 26 (26.5) 14 (30.4) 0.43
  Stroke 88 (21.0) 35 (16.8) 23 (23.5) 10 (21.7) 0.51
  Hypertension 200 (47.6) 106 (51.0) 49 (50.0) 27 (58.7) 0.51
  Dyslipidemia 72 (17.1) 41 (19.7) 19 (19.4) 12 (26.1) 0.48
  Diabetes 85 (20.2) 44 (21.2) 20 (20.4) 12 (26.1) 0.83
Number of other drugs §§ 2.9 ± 2.4 3.1 ± 2.5 3.0 ± 2.2 2.7 ± 2.7 0.80
  1. Results are expressed as mean ± standard deviation or as number of participants and (percentage). §defined as the practice of leisure time physical activity at least twice per week; §§non-antihypertensive drugs prescribed. BMI, body mass index;. Statistical analysis comparing all groups by Chi-square or one-way analysis of variance: NA, not assessable.