Table 3 Baseline blood pressure factors associated with antihypertensive drug changes, CoLaus study
From: Antihypertensive drug treatment changes in the general population: the colaus study
Continuers | Combiners | Switchers | Discontinuers | p-value | |
|---|---|---|---|---|---|
N | 420 (54.4) | 208 (26.9) | 98 (12.7) | 46 (6.0) | |
BP status baseline | |||||
SBP (mm Hg) | 137 ± 17 | 146 ± 19 | 138 ± 16 | 137 ± 15 | <0.001 |
DBP (mm Hg) | 83 ± 11 | 86 ± 12 | 83 ± 11 | 83 ± 9 | <0.05 |
Hypertension§ | 220 (52.4) | 138 (66.4) | 54 (55.1) | 20 (43.5) | <0.001 |
Antihypertensive drug | |||||
Diuretics (%) | 236 (56.2) | 64 (30.8) | 47 (48.0) | 15 (32.6) | <0.001 |
Beta-blockers (%) | 120 (28.6) | 50 (24.0) | 30 (30.6) | 16 (34.8) | 0.38 |
CCB (%) | 76 (18.1) | 42 (20.2) | 23 (23.5) | 5 (10.9) | 0.30 |
ACE inhibitors (%) | 119 (28.3) | 58 (27.9) | 32 (32.7) | 13 (28.3) | 0.84 |
ARBs (%) | 224 (53.3) | 82 (39.4) | 26 (26.5) | 13 (28.3) | <0.001 |
Treatment regimen (%) | |||||
One pill, single drug | 155 (36.9) | 132 (63.5) | 49 (50.0) | 32 (69.6) | |
One pill, combination | 119 (28.3) | 34 (16.4) | 26 (26.5) | 7 (15.2) | <0.001 |
Several pills | 146 (34.8) | 42 (20.2) | 23 (23.5) | 7 (15.2) |