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Figure 1 | BMC Pharmacology and Toxicology

Figure 1

From: Safety and pharmacological characterization of the molecular tweezer CLR01 – a broad-spectrum inhibitor of amyloid proteins’ toxicity

Figure 1

Schematic representation of the interaction between CLR01 and Lys. CLR01 is depicted in blue and Lys in black. The Coulombic attraction between a negatively charged phosphate group at the bridgehead of CLR01 and the positively charged ϵ-NH3 + group of Lys is illustrated in cyan. The binding is stabilized also by hydrophobic interaction between the hydrocarbon side arms of CLR01 and the butylene chain of the Lys.

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