TY - JOUR AU - Limson, B. M. AU - Romansky, M. J. PY - 1956 DA - 1956// TI - Novobiocin, a new antibiotic; laboratory and clinical evaluation of thirty patients with bacterial pneumonia JO - Antibiotic Med Clin Ther VL - 2 ID - Limson1956 ER - TY - JOUR AU - Gellert, M. AU - O’Dea, M. H. AU - Itoh, T. AU - Tomizawa, J. PY - 1976 DA - 1976// TI - Novobiocin and coumermycin inhibit DNA supercoiling catalysed by DNA gyrase JO - Proc Natl Acad Sci U S A VL - 73 UR - https://doi.org/10.1073/pnas.73.12.4474 DO - 10.1073/pnas.73.12.4474 ID - Gellert1976 ER - TY - JOUR AU - Sugino, A. AU - Higgins, N. P. AU - Brown, P. O. AU - Peebles, C. L. AU - Cozzarelli, N. R. PY - 1978 DA - 1978// TI - Energy coupling in DNA gyrase and the mechanism of action of novobiocin JO - Proc Natl Acad Sci U S A VL - 75 UR - https://doi.org/10.1073/pnas.75.10.4838 DO - 10.1073/pnas.75.10.4838 ID - Sugino1978 ER - TY - JOUR AU - Marcu, M. G. AU - Chadli, A. AU - Bouhouche, I. AU - Catelli, M. AU - Neckers, L. PY - 2000 DA - 2000// TI - The heat shock protein 90 antagonist novobiocin interacts with a previously unrecognized ATP-binding domain in the carboxyl terminus of the chaperone JO - J Biol Chem VL - 275 UR - https://doi.org/10.1074/jbc.M003701200 DO - 10.1074/jbc.M003701200 ID - Marcu2000 ER - TY - JOUR AU - Donnelly, A. AU - Blagg, B. S. J. PY - 2008 DA - 2008// TI - Novobiocin and additional inhibitors of the Hsp90 C-terminal nucleotide-binding pocket JO - Curr Med Chem VL - 15 UR - https://doi.org/10.2174/092986708786242895 DO - 10.2174/092986708786242895 ID - Donnelly2008 ER - TY - JOUR AU - Piper, P. W. AU - Millson, S. H. PY - 2012 DA - 2012// TI - Spotlight on the microbes that produce heat shock protein 90-targeting antibiotics JO - Open Biol VL - 2 UR - https://doi.org/10.1098/rsob.120138 DO - 10.1098/rsob.120138 ID - Piper2012 ER - TY - JOUR AU - Lorusso, G. AU - Ruegg, C. PY - 2008 DA - 2008// TI - The tumor microenvironment and its contribution to tumor evolution toward metastasis JO - Histochem Cell Biol VL - 130 UR - https://doi.org/10.1007/s00418-008-0530-8 DO - 10.1007/s00418-008-0530-8 ID - Lorusso2008 ER - TY - JOUR AU - Rӓsӓnen, K. AU - Vaheri, A. PY - 2010 DA - 2010// TI - Activation of fibroblasts in cancer stroma JO - Exp Cell Res VL - 316 UR - https://doi.org/10.1016/j.yexcr.2010.04.032 DO - 10.1016/j.yexcr.2010.04.032 ID - Rӓsӓnen2010 ER - TY - JOUR AU - Cirri, P. AU - Chiarugi, P. PY - 2012 DA - 2012// TI - Cancer-associated-fibroblasts and tumour cells: a diabolic liaison driving cancer progression JO - Cancer Metastasis Rev VL - 31 UR - https://doi.org/10.1007/s10555-011-9340-x DO - 10.1007/s10555-011-9340-x ID - Cirri2012 ER - TY - JOUR AU - Polanska, U. M. AU - Orimo, A. PY - 2013 DA - 2013// TI - Carcinoma-associated fibroblasts: non-neoplastic tumour-promoting mesenchymal cells JO - J Cell Physiol VL - 228 UR - https://doi.org/10.1002/jcp.24347 DO - 10.1002/jcp.24347 ID - Polanska2013 ER - TY - JOUR AU - Wright, W. E. PY - 1987 DA - 1987// TI - Periodontium destruction associated with oncology therapy. Five case reports JO - J Periodontol VL - 58 UR - https://doi.org/10.1902/jop.1987.58.8.559 DO - 10.1902/jop.1987.58.8.559 ID - Wright1987 ER - TY - JOUR AU - Epstein, J. B. AU - Thariat, J. AU - Bensadoun, R. J. AU - Barasch, A. AU - Murphy, B. A. AU - Kolnick, L. AU - Popplewell, L. AU - Maghami, E. PY - 2012 DA - 2012// TI - Oral complications of cancer and cancer therapy: from cancer treatment to survivorship JO - CA Cancer J Clin VL - 62 UR - https://doi.org/10.3322/caac.21157 DO - 10.3322/caac.21157 ID - Epstein2012 ER - TY - JOUR AU - Bresnick, E. H. AU - Dalman, F. C. AU - Sanchez, E. R. AU - Pratt, W. B. PY - 1989 DA - 1989// TI - Evidence that the 90-kDa heat shock protein is necessary for the steroid binding conformation of the L cell glucocorticoid receptor JO - J Biol Chem VL - 264 ID - Bresnick1989 ER - TY - JOUR AU - Jia, W. AU - Yu, C. AU - Rahmani, M. AU - Krystal, G. AU - Sausville, E. A. AU - Dent, P. AU - Grant, S. PY - 2003 DA - 2003// TI - Synergistic antileukemic interactions between 17-AAG and UCN-01 involve interruption of RAF/MEK – and AKT – related pathways JO - Blood VL - 102 UR - https://doi.org/10.1182/blood-2002-12-3785 DO - 10.1182/blood-2002-12-3785 ID - Jia2003 ER - TY - JOUR AU - Blagosklonny, M. V. AU - Toretsky, J. AU - Bohen, S. AU - Neckers, L. PY - 1996 DA - 1996// TI - Mutant conformation of p53 translated in vitro or in vivo requires functional HSP90 JO - Proc Natl Acad Sci U S A VL - 93 UR - https://doi.org/10.1073/pnas.93.16.8379 DO - 10.1073/pnas.93.16.8379 ID - Blagosklonny1996 ER - TY - JOUR AU - Kone, B. C. PY - 2000 DA - 2000// TI - Protein-protein interactions controlling nitric oxide synthases JO - Acta Physiol Scand VL - 168 UR - https://doi.org/10.1046/j.1365-201x.2000.00629.x DO - 10.1046/j.1365-201x.2000.00629.x ID - Kone2000 ER - TY - JOUR AU - Gao, Z. AU - Garcia-Echeverri, C. AU - Jensen, M. R. PY - 2010 DA - 2010// TI - Hsp90 inhibitors: clinical development and future opportunities in oncology therapy JO - Curr Opin Drug Discov Devel VL - 13 ID - Gao2010 ER - TY - JOUR AU - Geller, R. AU - Vignuzzi, M. AU - Andino, R. AU - Frydman, J. PY - 2007 DA - 2007// TI - Evolutionary constraints onchaperone – mediated folding provide an antiviral approach refractory to development of drug resistance JO - Genes Dev VL - 21 UR - https://doi.org/10.1101/gad.1505307 DO - 10.1101/gad.1505307 ID - Geller2007 ER - TY - JOUR AU - Isaacs, J. S. AU - Xu, W. AU - Neckers, L. PY - 2003 DA - 2003// TI - Heat shock protein 90 as a molecular target for cancer therapeutics JO - Cancer Cell VL - 3 UR - https://doi.org/10.1016/S1535-6108(03)00029-1 DO - 10.1016/S1535-6108(03)00029-1 ID - Isaacs2003 ER - TY - JOUR AU - Shahinas, D. AU - Liang, M. AU - Datti, A. AU - Pillai, D. R. PY - 2010 DA - 2010// TI - A repurposing strategy identifies novel synergistic inhibitors of Plasmodium falciparum heat shock protein 90 JO - J Med Chem VL - 53 UR - https://doi.org/10.1021/jm901796s DO - 10.1021/jm901796s ID - Shahinas2010 ER - TY - JOUR AU - Koka, S. AU - Reinhardt, R. A. PY - 1997 DA - 1997// TI - Periodontal pathogen-related stimulation indicates unique phenotype of primary cultured human fibroblasts from gingiva and periodontal ligament: implications for oral health disease JO - J Prosthet Dent VL - 77 UR - https://doi.org/10.1016/S0022-3913(97)70234-8 DO - 10.1016/S0022-3913(97)70234-8 ID - Koka1997 ER - TY - JOUR AU - Ara, T. AU - Kurata, K. AU - Hirai, K. AU - Uchihashi, T. AU - Uematsu, T. AU - Imamura, Y. AU - Furusawa, K. AU - Kurihara, S. AU - Wang, P. L. PY - 2009 DA - 2009// TI - Human gingival fibroblasts are critical in sustaining inflammation in periodontal disease JO - J Periodontal Res VL - 44 UR - https://doi.org/10.1111/j.1600-0765.2007.01041.x DO - 10.1111/j.1600-0765.2007.01041.x ID - Ara2009 ER - TY - JOUR AU - Weyermann, J. AU - Lochmann, D. AU - Zimmer, A. PY - 2005 DA - 2005// TI - A practical note on the use of cytotoxicity assays JO - Int J Pharm VL - 288 UR - https://doi.org/10.1016/j.ijpharm.2004.09.018 DO - 10.1016/j.ijpharm.2004.09.018 ID - Weyermann2005 ER - TY - JOUR AU - Calamia, V. AU - De Andrés, M. G. AU - Oreiro, N. AU - Ruiz-Romero, C. AU - Blanco, F. J. PY - 2011 DA - 2011// TI - Hsp90 inhibition modulates nitric oxide production and nitric oxide-induced apoptosis in human chondrocytes JO - BMC Musculoskelet Disord VL - 12 UR - https://doi.org/10.1186/1471-2474-12-237 DO - 10.1186/1471-2474-12-237 ID - Calamia2011 ER - TY - JOUR AU - Shelton, S. N. AU - Shawgo, M. E. AU - Matthews, S. B. AU - Lu, Y. AU - Donnelly, A. C. AU - Szabla, K. AU - Tanol, M. AU - Vielhauer, G. A. AU - Rajewski, R. A. AU - Matts, R. L. AU - Blagg, B. S. J. AU - Robertson, J. D. PY - 2009 DA - 2009// TI - KU135, a novel novobiocin-derived C-terminal inhibitor of the 90-kDa heat shock protein, exerts potent antiproliferative effects in human leukemic cells JO - Mol Pharmacol VL - 76 UR - https://doi.org/10.1124/mol.109.058545 DO - 10.1124/mol.109.058545 ID - Shelton2009 ER - TY - JOUR AU - Wu, L. X. AU - Xu, J. H. AU - Zhang, K. Z. AU - Lin, Q. AU - Huang, X. W. AU - Wen, C. X. AU - Chen, Y. Z. PY - 2008 DA - 2008// TI - Disruption of the Bcr-Abl/Hsp90 protein complex: a possible mechanism to inhibit Bcr-Abl-positive human leukemic blasts by novobiocin JO - Leukemia VL - 22 UR - https://doi.org/10.1038/leu.2008.89 DO - 10.1038/leu.2008.89 ID - Wu2008 ER - TY - JOUR AU - Kamal, A. AU - Thao, L. AU - Sensintaffar, J. AU - Zhang, L. AU - Boehm, M. F. AU - Fritz, L. C. AU - Burrows, F. J. PY - 2003 DA - 2003// TI - A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors JO - Nature VL - 425 UR - https://doi.org/10.1038/nature01913 DO - 10.1038/nature01913 ID - Kamal2003 ER - TY - JOUR AU - Le Bras, G. AU - Radanyi, C. AU - Peyrat, J. F. AU - Brion, J. D. AU - Alami, M. AU - Marsaud, V. AU - Stella, B. AU - Renoir, J. M. PY - 2007 DA - 2007// TI - New novobiocin analogues as antiproliferative agents in breast cancer cells and potential inhibitors of heat shock protein 90 JO - J Med Chem VL - 50 UR - https://doi.org/10.1021/jm0707774 DO - 10.1021/jm0707774 ID - Le Bras2007 ER - TY - JOUR AU - Schwab, B. L. AU - Guerini, D. AU - Didszun, C. AU - Bano, D. AU - Ferrando-May, E. AU - Fava, E. AU - Tam, J. AU - Xu, D. AU - Xanthoudakis, S. AU - Nicholson, D. W. AU - Carafoli, E. AU - Nicotera, P. PY - 2002 DA - 2002// TI - Cleavage of plasma membrane calcium pumps by caspases: a link between apoptosis and necrosis JO - Cell Death Differ VL - 9 UR - https://doi.org/10.1038/sj.cdd.4401042 DO - 10.1038/sj.cdd.4401042 ID - Schwab2002 ER - TY - JOUR AU - Skulachev, V. P. PY - 2006 DA - 2006// TI - Bioenergetic aspects of apoptosis, necrosis and mitoptosis JO - Apoptosis VL - 11 UR - https://doi.org/10.1007/s10495-006-5881-9 DO - 10.1007/s10495-006-5881-9 ID - Skulachev2006 ER - TY - STD TI - The pre-publication history for this paper can be accessed here:http://www.biomedcentral.com/2050-6511/15/25/prepub UR - http://www.biomedcentral.com/2050-6511/15/25/prepub ID - ref31 ER -