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Table 1 Liver phospholipid species quantified with LC-MS

From: Uridine prevents tamoxifen-induced liver lipid droplet accumulation

Phospholipid species (nmol/mg) C57BL/6J C57BL/6J + U C57BL/6J + Tmx C57BL/6J + Tmx + U
Lysophosphotidylcholine 6.7 ± 0.7 7.1 ± 0.3 7.4 ± 0.4 8.6 ± 0.8*
Phosphotidylcholine 380.5 ± 51 486.8 ± 20* 421.9 ± 30.6 495.1 ± 39.6*
Sphingomyelin & dihydrosphingomyelin 29.1 ± 3.7 40.0 ± 2.8* 50.3 ± 3.9* 50.2 ± 3.7*
Ether-linked phosphotidylcholine 18.9 ± 2.2 18.5 ± 0.6 21.2 ± 1.4 22.5 ± 2.1
Lysophosphoethanolamine 1.9 ± 0.1 2.3 ± 0.26 2.1 ± 0.2 2.6 ± 2.1
Phosphoethanolamine 105.5 ± 8.9 140.1 ± 8.8* 149.2 ± 8.3* 165.6 ± 8.9*
Phosphoethanoamine-ceramide 0.01 ± 0.01 0.01 ± 0.01 0.016 ± 0.005 0.027 ± 0.013
Ether-linked Phosphoethanoamine 4.0 ± 0.4 4.5 ± 0.3 4.5 ± 0.3 5.6 ± 0.4*
Phosphatidylinositol 51.2 ± 6.9 60.0 ± 7.1 46.9 ± 3.7 58.4 ± 6.2
Phosphatidylserine 15.4 ± 0.8 22.3 ± 1.1* 25.4 ± 1.3* 28.2 ± 1.3*
Ether-linked phosphatidylserine 0.2 ± 0.03 0.3 ± 0.03* 0.36 ± 0.017* 0.4 ± 0.04*
Phosphatidic acid 19.9 ± 2.3 23.2 ± 2.4 15.2 ± 1.7 21.2 ± 1.4
Phosphatidylglycerol 27.2 ± 3.1 29.9 ± 2.7 33.0 ± 2.1 29.7 ± 2.2
  1. Asterisks indicate p-value <0.05 versus untreated control.