Table 4 Logistic regression analysis of selected variables and adverse drug reactions to ART, ART clinic, Gondar University Hospital, June 2012
Variables | Total (N)* | Self-reported ADRs**(≥3), n = 229 | OR (95% CI)*** | P value | AOR( 95% CI)† |
|---|---|---|---|---|---|
Age | |||||
≤ 40 years | 327 | 192(58.7) | 1 | ||
>40 years | 57 | 37(64.9) | 1.28(0.69, 2.38) | 0.44 | |
Gender | |||||
Female | 257 | 152(59.1) | 1 | ||
Male | 127 | 77(60.6) | 1.06 (0.69, 1.64) | 0.78 | |
Education | |||||
Illiterate | 97 | 58(59.8) | 1 | ||
≥primary | 287 | 171(59.6) | 0.92 (0.58, 1.46) | 0.72 | |
Work status | |||||
Employed | 149 | 78(52.3) | 1 | 1 | |
Non-employed | 235 | 151(64.2) | 1.82 (1.17, 2.84) | <0.01 | 1.76 (1.15, 2.70)a |
Marital status | |||||
Married | 212 | 121(57.1) | 1 | ||
Non- married | 172 | 108(62.8) | 1.16 (0.75, 1.82) | 0.50 | |
Residency | |||||
Urban | 346 | 211(61.0) | 1 | ||
Rural | 38 | 18(43.4) | 0.58(0.28, 1.18) | 0. 14 | |
Duration of ART | |||||
≤4 years | 155 | 85(54.8) | 1 | ||
>4 years | 229 | 144(62.9) | 1.39 (0.92, 2.21) | 0.11 | |
ART treatment change | |||||
Yes | 78 | 42(53.8) | 1 | ||
No | 306 | 187(61.1) | 1.35(0.82,2.22) | 0.24 | |
Current CD4 level | |||||
≤350 | 181 | 107(59.1) | 0.96(0.64, 1.44) | 0.85 | |
>350 | 203 | 122(60.1) | 1 | ||
Current ART regimen | |||||
AZT backbone | 204 | 122(59.8) | 1.01(0.67, 1.53) | 0.94 | |
Non-AZT backbone | 180 | 107(59.4) | 1 | ||
Adherence | |||||
Yes | 370 | 223(60.3) | 1 | ||
No | 14 | 6(42.8) | 0.50(0.17, 1.45) | 0.2 | |
ADR duration (self-reported) | |||||
≤1 month | 212 | 140(66.0) | 1.81(1.20, 2.74) | 1.95(1.28,2.98)b | |
>1 month | 172 | 89(51.7) | 1 | <0.01 | 1 |