|
Variables
|
Total (N)*
|
Self-reported ADRs**(≥3), n = 229
|
OR (95% CI)***
|
P value
|
AOR( 95% CI)†
|
|---|
|
Age
| |
|
≤ 40 years
|
327
|
192(58.7)
|
1
| | |
|
>40 years
|
57
|
37(64.9)
|
1.28(0.69, 2.38)
|
0.44
| |
|
Gender
| |
|
Female
|
257
|
152(59.1)
|
1
| | |
|
Male
|
127
|
77(60.6)
|
1.06 (0.69, 1.64)
|
0.78
| |
|
Education
| |
|
Illiterate
|
97
|
58(59.8)
|
1
| | |
|
≥primary
|
287
|
171(59.6)
|
0.92 (0.58, 1.46)
|
0.72
| |
|
Work status
| |
|
Employed
|
149
|
78(52.3)
|
1
| |
1
|
|
Non-employed
|
235
|
151(64.2)
|
1.82 (1.17, 2.84)
|
<0.01
|
1.76 (1.15, 2.70)a
|
|
Marital status
| |
|
Married
|
212
|
121(57.1)
|
1
| | |
|
Non- married
|
172
|
108(62.8)
|
1.16 (0.75, 1.82)
|
0.50
| |
|
Residency
| |
|
Urban
|
346
|
211(61.0)
|
1
| | |
|
Rural
|
38
|
18(43.4)
|
0.58(0.28, 1.18)
|
0. 14
| |
|
Duration of ART
| |
|
≤4 years
|
155
|
85(54.8)
|
1
| | |
|
>4 years
|
229
|
144(62.9)
|
1.39 (0.92, 2.21)
|
0.11
| |
|
ART treatment change
| |
|
Yes
|
78
|
42(53.8)
|
1
| | |
|
No
|
306
|
187(61.1)
|
1.35(0.82,2.22)
|
0.24
| |
|
Current CD4 level
| |
|
≤350
|
181
|
107(59.1)
|
0.96(0.64, 1.44)
|
0.85
| |
|
>350
|
203
|
122(60.1)
|
1
| | |
|
Current ART regimen
| |
|
AZT backbone
|
204
|
122(59.8)
|
1.01(0.67, 1.53)
|
0.94
| |
|
Non-AZT backbone
|
180
|
107(59.4)
|
1
| | |
|
Adherence
| |
|
Yes
|
370
|
223(60.3)
|
1
| | |
|
No
|
14
|
6(42.8)
|
0.50(0.17, 1.45)
|
0.2
| |
|
ADR duration (self-reported)
| |
|
≤1 month
|
212
|
140(66.0)
|
1.81(1.20, 2.74)
| |
1.95(1.28,2.98)b
|
|
>1 month
|
172
|
89(51.7)
|
1
|
<0.01
|
1
|
-
*Percent frequency that refers to the total number of patients (N = 384). **Number and proportion of patients’ self-reporting 3 or more adverse drug reactions. ***Values represent odds ratio (OR) at 95% confidence interval. †Values represent adjusted odds ratio (AOR) at 95% confidence interval, ap = 0.01, bp = 0.001.
