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Table 5 Impacts of self-reported ADRs on perception of treatment and social interaction, ART clinic, Gondar University Hospital, June 2012

From: Self-reported adverse drug reactions and their influence on highly active antiretroviral therapy in HIV infected patients: a cross sectional study

Variables n (%) Association of variables with specific ADRs (chi-square or fisher test)
   Nausea Headache Fever Vomiting Lethargy Loss of appetite Insomnia Depression Night mare Diarrhea OU/DM
Impacts on patients perception on treatment patients who:           
Decided to skip medication due to ADRs* 10 (2.6) 0.54 0.51 0.35 0.55 0.26 0.48 0.20 0.21 0.42 0.78 0.26
Consider ART unsuccessful due to ADRs** 114 (31.0) 1.43 0.10 7.42b 5.00a 29.53c 25.93 c 14.47 c 24.43c 1.43 13.63c 13.70c
Impacts of ADR on patients’ social interaction patients who:           
Perceive that people avoid them due to observed ADRs** 21 (32.9) 5.68 a 0.76 11.97c 12.7c 28.13c 26.67 c 18.28 c 23.15c 3.19a 8.45b 14.94c
Tend to reduce/avoid social interaction because of ADRs** 119 (32.2) 2.11 0.26 9.87 c 7.96b 33.20 26.67c 20.88 c 3.40c 1.87 8.45b 6.70 c
Perceive family members avoid them when ADRs occurred ** 57 (15.4) 0.99 3.35a 2.19 0.06 0.08 1.01 0.45 3.40a 0.03 0.99 6.70b
Talk to family members about ADRs as it appears** 296 (80.0) 14.32c 10.24c 5.92 b 7.73b 4.34a 2.84 0.61 2.21 0.31 0.01 0.62
  1. n = 384. *Fishers exact test, **chi-square test was used to assess associations. asignificant at a level of p < 0.05, bsignificant at a level of p < 0.01, csignificant at a level of p < 0.001. OU/DM, oral ulceration or dry mouth.