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Table 2 Mean (±SD) CLam/W a , CLcr b , V/W c and T½ d for amoxicillin in patients using amoxicillin/clavulanic acid broken down per age group

From: Is the standard dose of amoxicillin-clavulanic acid sufficient?

Age group in years N CLam/W in L/h/kg CLcr in mL/min V/W in L/kg T½ in h
<70 31 0.19 (±0.08) 82 (±25) 0.30 (±0.06) 1.26 (±0.44)
>70 26 0.14 (±0.06) 55 (±19) 0.32 (±0.08) 1.83 (±0.71)
P-value   0.02 <0.01 0.82 <0.01
  1. aCLam/W: amoxicillin clearance corrected for bodyweight.
  2. bCLcr: creatinine clearance.
  3. cV/W: volume of distribution corrected for bodyweight.
  4. dT½: amoxicillin half life.