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Table 2 Multivariate linear regression of the interaction between the change in NPS (0-10) during the CPM-TASK by the treatment group considering the BDNF and pain thresholds (n = 63)

From: Melatonin analgesia is associated with improvement of the descending endogenous pain-modulating system in fibromyalgia: a phase II, randomized, double-dummy, controlled trial

Parameters Β t P 95% CI
Dependent variable: CPM-TASK     
  9.0 1.14 0.01 (4.33 to 32.35)
Treatment group     
  Melatonin + Amitriptyline -1.27 -1.72 0.09 (-2.76 to 0.21)
  Melatonin -1.75 -2.5 0.01 (-3.18 to-0.31)
  Amitriptyline 0b(reference)    
BDNF (ng/mL) -0.28 -2.23 0.01 (-0.53 to-0.04)
Heat pain threshold -8.06 -2.49 0.01 (-14.56 to-1.55)
Interaction     
  Serum BDNF (ng/mL) vs. PPT Pain pressure threshold (Kgf/cm2) 0.12 2.07 0.04 (0.04 to 0.24)
  1. bindicates the reference category used to do the comparisons.