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Table 1 Baseline patient demographics and clinical characteristics

From: Palonosetron versus ondansetron as rescue medication for postoperative nausea and vomiting: a randomized, multicenter, open-label study

  Palonosetron Ondansetron Total
  (n = 48) (n = 50) (N = 98)
Age (y)    
  Mean (SD) 41 (10.2) 43 (13.8) 42 (12.1)
  Min, max 22, 62 21, 83 21, 83
Sex    
  Female, n (%) 48 (100.0) 50 (100.0) 98 (100.0)
Race, n (%)    
  White 36 (75.0) 36 (72.0) 72 (73.5)
  Black or African American 7 (14.6) 9 (18.0) 16 (16.3)
  Asian 1 (2.1) 3 (6.0) 4 (4.1)
  Other 4 (8.3) 2 (4.0) 6 (6.1)
Nonsmoker*, n (%) 45 (93.8) 49 (98.0) 94 (95.9)
BMI (kg/m2)    
  Mean (SD) 27.2 (5.4) 27.8 (5.0) 27.5 (5.2)
  Min, max 17, 38 20, 39 17, 39
Duration of laparoscopic surgery (min)    
  Mean (SD) 113.3 (69.4) 102.0 (59.8) 107.6 (64.6)
  Median 92.5 81.5 88.5
  Min, max 26, 306 34, 282 26, 306
Baseline NRS for nausea severity    
  n 47 48 95
  Mean (SD) 5.7 (1.84) 5.9 (1.86) 5.8 (1.84)
  Min, max 2, 10 3, 10 2, 10
History of PONV, n (%) 30 (62.5) 27 (54.0) 57 (58.2)
Type of laparoscopic surgery, n (%)    
  Gynecological 37 (77.1) 31 (62.0) 68 (69.4)
  Abdominal 11 (22.9) 19 (38.0) 30 (30.6)
ASA classification, n (%)    
  I 20 (41.7) 20 (40.0) 40 (40.8)
  II 25 (52.1) 24 (48.0) 49 (50.0)
  III 3 (6.3) 6 (12.0) 9 (9.2)
Baseline opioid use, n (%) 47 (97.9) 50 (100.0) 97 (99.0)
  1. Abbreviations: ASA American Society of Anesthesiologists, BMI body mass index, NRS Numeric Rating Scale, PONV postoperative nausea and vomiting, SD standard deviation.
  2. *Never smoked or quit ≥12 months before participation in the study. History of PONV and/or currently prone to motion sickness.