|
Detection limits
|
---|
|
Experiment 1
|
Experiment 2
|
Experiment 3
|
PyroDetect System
|
---|
|
n = 6 – 9
|
n = 6
|
n = 5
|
Poolblood
|
---|
LPS E.coli
|
0.08 EU/ml
|
0.04 EU/ml
|
0.08 EU/ml
|
0.04 EU/ml ‡
|
0127:B8
|
LPS E.coli
|
not tested
|
0.5 EU/ml
|
0.25 EU/ml
|
0.25 EU/ml
|
0113:H10
|
Peptidoglycan
|
10 μg/ml
|
50 μg/ml
|
10 μg/ml
|
1 μg/ml ‡
|
Bac. subtilis
|
Lipoteichoic acid
|
10 μg/ml
|
10 μg/ml
|
10 μg/ml
|
1 μg/ml ‡
|
Staph. aureus
| | | | |
- Different animals were used, permutation test, compared to unstimulated blood. Experiment 3 was the comparison with the PyroDetect System. ‡ = lowest concentration tested.