Skip to main content

Table 2 Blood pH and gases in the different groups

From: Evaluation of lung recovery after static administration of three different perfluorocarbons in pigs

 

Baseline (Anesthetized)

Time after perfluorocarbon administration (h)

1 (Anesthetized)

12 (Anesthetized)

48 (Awake)

96 (Awake)

Number of animals (n)

     

  Control

4

4

4

4

4

  PFD

4

4

4

3*

3*

  PFOC

4

4

4

4

4

  PFOB

4

4

4

4

4

Blood pH

     

  Control

7.45 ± 0.04

7.43 ± 0.03

7.42 ± 0.02

7.37 ± 0.05

7.36 ± 0.02

  PFD

7.47 ± 0.02

7.45 ± 0.04

7.43 ± 0.03

7.29 ± 0.11

7.23 ± 0.09

  PFOC

7.47 ± 0.01

7.57 ± 0.02

7.45 ± 0.03

7.31 ± 0.07

7.36 ± 0.03

  PFOB

7.45 ± 0.01

7.53 ± 0.02

7.40 ± 0.03

7.32 ± 0.05

7.38 ± 0.04

pO 2 (mmHg)

     

  Control

126 ± 6

118 ± 8

115 ± 4

103 ± 2

103 ± 2

  PFD

146 ± 4

98 ± 7

90 ± 13

84 ± 11

79 ± 9

  PFOC

137 ± 4

100 ± 4

113 ± 8

95 ± 3

93 ± 5

  PFOB

125 ± 3

82 ± 5

95 ± 12

92 ± 9

95 ± 6

pCO 2 (mmHg)

     

  Control

43 ± 4

45 ± 2

47 ± 4

40 ± 3

38 ± 2

  PFD

40 ± 3

43 ± 7

43 ± 4

44 ± 2

57 ± 11

  PFOC

37 ± 2

30 ± 2

43 ± 4

43 ± 2

43 ± 2

  PFOB

40 ± 1

35 ± 1

46 ± 5

40 ± 2

43 ± 5

  1. PFD, perflurodecalin; PFOC, perfluoro-N-octane; PFOB, perfluorooctylbromide; *, One animal was euthanized for respiratory distress at t = 24 h in the PFD group; p < 0.05 vs corresponding value in the Control group; p < 0.05 vs corresponding value in the PFD group.