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Figure 3 | BMC Pharmacology and Toxicology

Figure 3

From: Randomized pharmacokinetic evaluation of different rifabutin doses in African HIV- infected tuberculosis patients on lopinavir/ritonavir-based antiretroviral therapy

Figure 3

25-O-desacetylrifabutin median concentration-time profiles. Median 25-O-desacetylrifabutin (d-RBT) concentrations for the three pharmacokinetic evaluations in 14 patients. The bars represent interquartile range (IQR). The blue line corresponds to the dosing of RBT at 300 mg without ART; the red line to RBT dosing at 150 mg tiw with LPV/r based ART and the purple line to dosing with 150 mg of RBT daily.

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