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Table 3 The maximum grade of sCr increased and anorexia in each group

From: Magnesium supplementation and high volume hydration reduce the renal toxicity caused by cisplatin-based chemotherapy in patients with lung cancer: a toxicity study

Grade (n/%) High-volume hydration Mg- (n = 41) High-volume hydration Mg+ (n = 27) Low-volume hydration Mg+ (n = 17) P value (High Mg- vs High Mg+) P value (High Mg- vs Low Mg+)
  sCr     
0 0 (0) 1 (3.7) 1 (5.9) <0.001 0.002
1 22 (53.6) 26 (96.3) 15 (88.2)   
2 17 (41.5) 0 (0) 1 (5.9)   
3 2 (4.9) 0 (0) 0 (0)   
  anorexia     
< 2 33 (80.4) 21 (77.8) 14 (82.4) 0.787 0.592
≥ 2 8 (19.5) 6 (22.2) 3 (17.6)   
  1. The maximum grade of sCr increase was assessed using the Common Terminology Criteria for Adverse Events Version 4.0 (CTCAE v4.0).