Magnesium supplementation and high volume hydration reduce the renal toxicity caused by cisplatin-based chemotherapy in patients with lung cancer: a toxicity study

Table 4 The comparison between pre and post sCr, and CrCl in each group

	Pre sCr	Post sCr	P value	Pre CrCl	Post CrCl	P value
	(mg/dl)	(mg/dl)	P value	(ml/min)	(ml/min)	P value
High-volume hydration Mg-	0.75	0.92	<0.001	78.88	65.99	<0.001
High-volume hydration Mg-	(0.64 to 0.92)	(0.79 to 1.21)	<0.001	(70.37 to 95.64)	(48.62 to 80.13)	<0.001
High-volume hydration Mg+	0.71	0.71	0.118	73.21	73.66	0.254
High-volume hydration Mg+	(0.58 to 0.84)	(0.63 to 0.84)	0.118	(67.93 to 104.61)	(64.39 to 100.65)	0.254
Low-volume hydration Mg+	0.72	0.73	0.068	83.59	76.99	0.055
Low-volume hydration Mg+	(0.68 to 0.78)	(0.70 to 0.85)	0.068	(72.51 to103.63)	(72.22 to 85.69)	0.055

Median (interquartile range). sCr, serum creatinine; CrCl, creatinine clearance.

ISSN: 2050-6511