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Table 3 Drug classes related to an adverse drug event (ADE), by anatomical therapeutic chemical classification (ATC)

From: Adverse drug events identified by triggers at a teaching hospital in Brazil

ATC codea Number of prescriptions of the drug class Number of prescriptions of the drug class associated with an ADEb Proportion (%)
A - Alimentary tract and metabolism 478 10 2.09
  A02 - Drugs for acid related disorders 197 7 3.6
  A03 - Drugs for functional gastrointestinal disorders 182 1 0.6
  A06 – Laxatives 15 1 6.7
  A10 - Drugs used in diabetes 59 1 1.7
B - Blood and blood forming organs 354 7 2.0
  B01 - Antithrombotic agents 228 6 2.6
  B05 - Plasma substitutes and perfusion solutions 102 1 1.0
C - Cardiovascular system 277 5 1.8
  C03 – Diuretics 69 2 2.9
  C09 - Agents acting on the renin-angiotensin system 79 2 2.5
  C10 - Lipid modifying agents 28 1 3.6
H - Systemic hormonal prep, excluding sex hormones 44 1 2.3
  H02 - Corticosteroids for systemic use 44 1 2.3
J - General antiinfectives for systemic use 405 13 3.2
  J01 - Antibacterials for systemic use 387 10 2.6
  J02 - Antimycotics for systemic use 7 3 42.9
M - Musculo-skeletal system 177 1 0.6
  M01 - Antiinflammatory and antirheumatic products 168 1 0.6
N - Nervous system 566 15 2.7
  N02 – Analgesics 419 9 1.7
  N03 – Antiepileptics 40 2 5.0
  N05 – Psycholeptics 82 3 6.1
  N06 - Psychoanaleptics 11 1 9.1
P - Antiparasitic products 8 1 12.5
  P01 – Antiprotozoals 2 1 50.0
Unclassified drug 9 1 11.1
Total 2499 54 2.2
  1. aThe first and second level of the Anatomical Therapeutic Chemical Classification (ATC) associated with at least one ADE.
  2. bNumber of ADE-drugs is greater (54) than number of ADEs (44), because one drug can be associated with several ADEs.